1. Diffusion
In brief:Diffusion is the passive movement of a substance from an area of high concentration to an area of low concentration.
Diffusion is the passive movement of a substance (solute) from an area of high concentration to an area of low concentration. No energy is required - it is a passive process.
Examples: CO₂ diffusing out of a fizzy drink; perfume spreading through a room; oxygen diffusing into blood in the lungs.
Factors Affecting Rate of Diffusion
- Concentration gradient - the greater the difference, the faster diffusion occurs
- Temperature - higher temperature = more energy = faster diffusion
- Surface area - greater surface area of the membrane = faster diffusion
- Distance - greater distance = slower diffusion (limits cell size)
Only small molecules (O₂, CO₂) move by diffusion. Large molecules like proteins require energy.
Fluid-mosaic model of the plasma membrane
Wikimedia Commons (CC)

Osmosis across a semi-permeable membrane
Wikimedia Commons (CC)
Key Points
- 1Diffusion is passive movement from high to low concentration
- 2No energy required - moves 'down the concentration gradient'
- 3Rate increases with: larger gradient, higher temperature, greater surface area
- 4Greater distance = slower diffusion - this limits cell size
- 5Only small molecules diffuse across membranes
Learning Outcomes
- Distinguish between diffusion, osmosis and active transport; examine the role of osmosis in food preservation and plant health